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Michael Smith Biography Beginning of Paper Smith, Michael (1932- ), British-born Canadian biochemist and Nobel Prize winner. Smith developed a method for altering the nucleic acid deoxyribonucleic acid (DNA) structure of protein molecules. His technique enabled scientists to determine with great accuracy the function of prote .... Middle of Paper .... perform a variety of crucial chemical functions in plants and animals. The best way to study the function of a specific protein is to mutate it, then observe how this changes the behavior of the entire organism. Prior to Smith's innovation, mutation was achieved by exposing random cells to mutagens (radiation or chemicals). This approach was unreliable because both radiation and chemicals mutated proteins randomly, making it impossible to determine how specific proteins had been affected. Scientists needed a way to deliberately alter a pro .... 437 words | 2 pages Subscription Length Price Join 30 days membership (recurring) $19.95 90 days membership (recurring) $39.95 180 days membership (non-recurring) $69.95