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Genetics And Evolution: Cystic Fibrosis And Down Syndrome Beginning of Paper Cystic Fibrosis Cystic Fibrosis is a disorder where the exocrine glands secrete abnormally thick mucus, leading to obstruction of the pancreas and chronic infections of the lungs, which usually cause death in childhood or early adulthood. Some mildly affected patients may survive lo .... Middle of Paper .... occurring about once in every 2500 births. If both parents carry the gene responsible for the disease, they have a one-in-four chance of having an affected child. In 1989, the gene responsible for cystic fibrosis was identified on chromosome 7 (out of 23 chromosomes). Since that time more than 200 different mutations in the cystic fibrosis gene have been described, and tests have been developed to detect the most common alterations. These tests can identify unaffected carriers of the disorder. Sickle-Cell Anemia Sickle-Cell Anemia, also .... 998 words | 4 pages Subscription Length Price Join 30 days membership (recurring) $19.95 90 days membership (recurring) $39.95 180 days membership (non-recurring) $69.95